Downtown / Gaslamp Quarter
$$$ · walkable · $40–60 parking
The default answer for a first trip. Petco Park, the Embarcadero, USS Midway, Seaport Village and hundreds of restaurants are on foot, the trolley runs to Old Town and Santa Fe Depot, and the airport is seven minutes away. Downside: parking costs and Gaslamp noise on weekend nights.
Local tip: Book on the quieter edges — Marina District or East Village — rather than on Fifth Avenue if you want to sleep.
